A-LiNK: Improving Outcomes in Autoimmune Liver Disease
Observational · No treatment assigned · 8 sites · Children's Hospital Medical Center, Cincinnati
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
Condition(s) listed: Autoimmune Hepatitis and Primary Sclerosing Cholangitis. This is an observational study: researchers collect information (for example questionnaires, samples, or scans) but the study does not assign a treatment.
Who can join
- Age range not stated in the record
- Any sex
Some of the main requirements, copied from the record:
- Clinical diagnosis of autoimmune hepatitis (AIH)
- Clinical diagnosis of primary sclerosing cholangitis (PSC)
- Clinical diagnosis of autoimmune sclerosing cholangitis (ASC)
There are also 1 reasons someone might not be able to join (exclusion criteria). Only the trial team can confirm whether you qualify.
What's involved
- About 800 participants are expected to take part.
- The study has 1 group.
- Start date: 2022-04-28.
- Main results expected around 2032-12-31 (estimate from the record).
- 8 study sites listed (8 marked recruiting) in United States.
Groups in this study
- Children and adolescents with Autoimmune Liver Disease
Main thing being measured
- Baseline disease characteristics in the population (2034)
- Disease relapse and biochemical remission rates (2034)
- Complications of disease (2034)
In the researchers’ words
The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD). This study will establish a shared clinical registry and a learning health network for the participating sites focusing on collecting and transmitting clinical measurement data, information about processes, and participation in an…
Words you might see
- Remission: a period when the disease is quiet or under control.
- Autoimmune hepatitis: a liver disease where the immune system attacks the liver.
General definitions, not specific to this trial.
This summary was written automatically from the official record using fixed templates (no AI), so it only says what the record says, and may leave things out.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Recruiting |
|---|---|
| Phase | Observational |
| Study type | Observational |
| Conditions | Autoimmune Hepatitis; Primary Sclerosing Cholangitis |
| Lead sponsor | Children's Hospital Medical Center, Cincinnati |
| Enrollment | 800 (estimated) |
| Start date | 2022-04-28 |
| Primary completion (est.) | 2032-12-31 |
| First posted | 2023-03-01 |
| Last updated | 2026-08-19 |
| Official title | Autoimmune Liver Disease Network for Kids (A-LiNK): Using Patient Data to Transform Care and Improve Outcomes for Children, Adolescents, and Young Adults With Autoimmune Liver Disease |
| ClinicalTrials.gov ID | NCT05750498 |
Interventions
- No interventions (Other)
There are no interventions
Full eligibility criteria (from the record)
Inclusion Criteria: * Clinical diagnosis of autoimmune hepatitis (AIH) * Clinical diagnosis of primary sclerosing cholangitis (PSC) * Clinical diagnosis of autoimmune sclerosing cholangitis (ASC) Exclusion Criteria: • History of liver transplant
Locations (8)
| Site | City | Country | Site status |
|---|---|---|---|
| Stanford University | Palo Alto, California | United States | Recruiting |
| Riley Children's Health | Indianapolis, Indiana | United States | Recruiting |
| St. Louis Children's Hospital | St Louis, Missouri | United States | Recruiting |
| Cincinnati Children's Hospital Medical Center | Cincinnati, Ohio | United States | Recruiting |
| Nationwide Children's Hospital | Columbus, Ohio | United States | Recruiting |
| UPMC Children's Hospital of Pittsburgh | Pittsburgh, Pennsylvania | United States | Recruiting |
| UT Southwestern Medical Center | Dallas, Texas | United States | Recruiting |
| Seattle Children's Hospital | Seattle, Washington | United States | Recruiting |
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.