Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)
Observational · No treatment assigned · 1 site · Seattle Children's Hospital
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
Condition(s) listed: Inflammatory Bowel Diseases, Crohn Disease and Ulcerative Colitis. This is an observational study: researchers collect information (for example questionnaires, samples, or scans) but the study does not assign a treatment.
Who can join
- Ages 6 to 21
- Any sex
Some of the main requirements, copied from the record:
- Suspected diagnosis of CD (Crohn's Disease), UC (Ulcerative Colitis) or Indeterminate colitis (IC)
There are also 4 reasons someone might not be able to join (exclusion criteria). Only the trial team can confirm whether you qualify.
What's involved
- About 200 participants are expected to take part.
- Start date: 2024-05-10.
- Main results expected around 2028-01 (estimate from the record).
- 1 study site listed (1 marked recruiting) in United States.
Main thing being measured
- Bio-repository sample collection for spatial transcriptomics (3 years)
In the researchers’ words
This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with disorders of the brain-gut interactions (DBGI) with no detectable gut inflammation.
This is a short automatic summary built from the official record. A fuller plain-English card is coming; until then, please read the official record.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Recruiting |
|---|---|
| Phase | Observational |
| Study type | Observational |
| Conditions | Inflammatory Bowel Diseases; Crohn Disease; Ulcerative Colitis; Indeterminate Colitis; Functional Abdominal Pain Syndrome; Functional Bowel Disorder; Esophageal Diseases; Gastroduodenal Disorder; Bowel Dysfunction; Gallbladder Diseases; Sphincter of Oddi Dysfunction; Anorectal Disorder |
| Lead sponsor | Seattle Children's Hospital |
| Collaborators | Allen Institute |
| Enrollment | 200 (estimated) |
| Start date | 2024-05-10 |
| Primary completion (est.) | 2028-01 |
| First posted | 2024-03-18 |
| Last updated | 2026-04-24 |
| Official title | Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation |
| ClinicalTrials.gov ID | NCT06315179 |
Interventions
- Esophagogastroduodenoscopy (EGD) with biopsy (Diagnostic Test)
Esophagogastroduodenoscopy (EGD) is a test procedure to examine the lining of the esophagus, stomach, and first part of the small intestine. - Colonoscopy w/ biopsy (Diagnostic Test)
Colonoscopy is a test procedure to examine the lining of the different portions of the large intestine: cecum, colon, rectum, and anal canal.
Full eligibility criteria (from the record)
Inclusion Criteria: * Suspected diagnosis of CD (Crohn's Disease), UC (Ulcerative Colitis) or Indeterminate colitis (IC) Exclusion Criteria: * Evidence of Other Complicating Medical Issues: * Other serious medical conditions, such as neurological, liver, kidney, or systemic disease * Pregnancy * Tobacco, alcohol, or illicit drug abuse
Locations (1)
| Site | City | Country | Site status |
|---|---|---|---|
| Seattle Children's Hospital | Seattle, Washington | United States | Recruiting |
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.