Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome
Observational · No treatment assigned · 1 site · Chungnam National University Hospital
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
Condition(s) listed: Autoimmune Hepatitis, Primary Sclerosing Cholangitis and Non-Alcoholic Fatty Liver Disease. This is an observational study: researchers collect information (for example questionnaires, samples, or scans) but the study does not assign a treatment.
Who can join
- Ages 19 and older
- Any sex
- Healthy volunteers accepted
Some of the main requirements, copied from the record:
- Adults aged 19 years and older diagnosed with autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, non-alcoholic fatty liver disease, or liver abscess, who have consented to participate in this study at…
- Adults aged 19 years and older, who are cohabitants of patients diagnosed with autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, non-alcoholic fatty liver disease, or liver abscess, and have consented to…
- B. Exclusion
There are also 2 reasons someone might not be able to join (exclusion criteria). Only the trial team can confirm whether you qualify.
What's involved
- About 3000 participants are expected to take part.
- Start date: 2024-07-08.
- Main results expected around 2029-07-08 (estimate from the record).
- 1 study site listed (1 marked recruiting) in South Korea.
Main thing being measured
- Chi-square test (Before treatment, 3~12months after treatment)
- t-test (Before treatment, 3~12months after treatment)
- Pearson's coefficient (Before treatment, 3~12months after treatment)
In the researchers’ words
In this study, we aim to identify gut microbiomes specific to patients with chronic refractory liver disease and to conduct a gut-liver axis study on the pathogenesis and disease progression.
Words you might see
- PBC: primary biliary cholangitis, a different chronic bile-duct disease.
- Autoimmune hepatitis: a liver disease where the immune system attacks the liver.
General definitions, not specific to this trial.
This summary was written automatically from the official record using fixed templates (no AI), so it only says what the record says, and may leave things out.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Recruiting |
|---|---|
| Phase | Observational |
| Study type | Observational |
| Conditions | Autoimmune Hepatitis; Primary Sclerosing Cholangitis; Non-Alcoholic Fatty Liver Disease; Liver Abscess; Primary Biliary Cirrhosis |
| Lead sponsor | Chungnam National University Hospital |
| Collaborators | Chungnam National University |
| Enrollment | 3000 (estimated) |
| Start date | 2024-07-08 |
| Primary completion (est.) | 2029-07-08 |
| First posted | 2024-07-25 |
| Last updated | 2026-03-20 |
| Official title | Exploration of Liver-gut Axis Through Identification of Liver Disease-specific Microbiome |
| ClinicalTrials.gov ID | NCT06519162 |
Interventions
- None listed
Full eligibility criteria (from the record)
Inclusion Criteria: * Adults aged 19 years and older diagnosed with autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, non-alcoholic fatty liver disease, or liver abscess, who have consented to participate in this study at Chungnam National University Hospital. * Adults aged 19 years and older, who are cohabitants of patients diagnosed with autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, non-alcoholic fatty liver disease, or liver abscess, and have consented to participate in this study at Chungnam National University Hospital. B. Exclusion Exclusion Criteria: * Individuals under the age of 19. * Patients or guardians who do not consent to participate in the study
Locations (1)
| Site | City | Country | Site status |
|---|---|---|---|
| Chungnam National University Hospita | Daejeon, Jung-gu | South Korea | Recruiting |
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.