WAter Preparation in Crohn's Disease's Imagery
Not applicable · Testing water preparation and polyethylene glycol preparation · 1 site · University Hospital, Toulouse
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
This study is testing water preparation and polyethylene glycol preparation as a way to diagnose or measure disease. Condition(s) listed: Crohn Disease (CD).
Participants are assigned to groups by chance (randomized).
It is single-blind: participants do not know which group they are in.
This study does not use drug-development phases (it may test a device, diet, procedure, app, or care approach).
Who can join
- Ages 18 and older
- Any sex
Some of the main requirements, copied from the record:
- Diagnosis of Crohn's Disease,
- need for MRE (determined by patient's gastroenterologist)
There are also 5 reasons someone might not be able to join (exclusion criteria). Only the trial team can confirm whether you qualify.
What's involved
- About 194 participants are expected to take part.
- Start date: 2025-01-29.
- Main results expected around 2026-12-01 (estimate from the record).
- 1 study site listed (1 marked recruiting) in France.
Main thing being measured
- Bowel distension (The day of the Magnetic Resonance Enterography (MRE), specifically during the imaging procedure : from ingestion of…)
In the researchers’ words
The goal of this clinical trial is to compare distension quality and patient experience of water and polyethylene glycol preparation as oral contrast media in Magnetic Resonance Enterography (MRE) in patients with Crohn's disease. Thus, the main question it aims to answer is: Is water sufficient to interpret MRE from patients with Crohn's disease?
This is a short automatic summary built from the official record. A fuller plain-English card is coming; until then, please read the official record.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Recruiting |
|---|---|
| Phase | Not applicable |
| Study type | Interventional |
| Conditions | Crohn Disease (CD) |
| Lead sponsor | University Hospital, Toulouse |
| Enrollment | 194 (estimated) |
| Start date | 2025-01-29 |
| Primary completion (est.) | 2026-12-01 |
| First posted | 2024-11-15 |
| Last updated | 2026-05-08 |
| Official title | WAter Preparation for Magnetic Resonance Enterography in Crohn's Disease |
| ClinicalTrials.gov ID | NCT06690632 |
Interventions
- water preparation (Other)
ingestion of 1.5L of water 30min prior MRE acquisition - polyethylene glycol preparation (Other)
ingestion of 1.5L of water diluted PEG 45 min prior MRE acquisition (standard protocol)
Full eligibility criteria (from the record)
Inclusion criteria: * Diagnosis of Crohn's Disease, * need for MRE (determined by patient's gastroenterologist) Exclusion criteria: * < 18 years old, * inability to obtain an informed consent, * patient under guardianship or curatorship, allergy to PEG, * contraindication to MRE (pregnancy, pace maker, claustrophobia in particular), - contraindication to phloroglucinol administration (phenylcetonuria), * contraindication to gadolinium administration (kidney failure with glomerular filtration rate < 30/mL/1.73m², pregnancy, allergy).
Locations (1)
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Toulouse | Toulouse | France | Recruiting |
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.