Unraveling the Blood Microbiome in Postoperative Recurrence of Crohn's Disease
Observational · No treatment assigned · 1 site · Erasmus Medical Center
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
Condition(s) listed: Crohn's Disease (CD). This is an observational study: researchers collect information (for example questionnaires, samples, or scans) but the study does not assign a treatment.
Who can join
- Ages 16 and older
- Any sex
- Healthy volunteers accepted
Some of the main requirements, copied from the record:
- Diagnosis of Crohn's Disease
- Adult ≥ 16 years
- Undergoing an ileocolonic resection or reresection
Plus 1 more requirement(s). There are also 3 reasons someone might not be able to join (exclusion criteria). Only the trial team can confirm whether you qualify.
What's involved
- About 70 participants are expected to take part.
- Start date: 2025-02 (planned).
- Main results expected around 2026-08 (estimate from the record).
- 1 study site listed in Netherlands.
Main thing being measured
- Differences in bloodmicrobiome between recurrence & non recurrence patients. (From enrollment to the postoperative endoscopy (at 6 months follow-up).)
In the researchers’ words
Crohn's disease, a chronic inflammation of the gastro-intestinal tract, is a disease with a complex pathogenetic background. Hereditary factors, environmental factors and the gut flora play a varying role in its onset, however, this role remains unclear to date.
This is a short automatic summary built from the official record. A fuller plain-English card is coming; until then, please read the official record.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Not yet recruiting |
|---|---|
| Phase | Observational |
| Study type | Observational |
| Conditions | Crohn's Disease (CD) |
| Lead sponsor | Erasmus Medical Center |
| Enrollment | 70 (estimated) |
| Start date | 2025-02 |
| Primary completion (est.) | 2026-08 |
| First posted | 2025-01-13 |
| Last updated | 2025-01-13 |
| Official title | Unraveling the Blood Microbiome in Postoperative Recurrence of Crohn's Disease |
| ClinicalTrials.gov ID | NCT06770140 |
Interventions
- None listed
Full eligibility criteria (from the record)
Inclusion Criteria: * Diagnosis of Crohn's Disease * Adult ≥ 16 years * Undergoing an ileocolonic resection or reresection * Written informed consent Exclusion Criteria: * Use of antibiotics in the past 8 weeks at the timepoints when blood is withdrawn and feces is collected. * Use of probiotics in the past 8 weeks at the timepoints when blood is withdrawn and feces is collected. * Not willing to collect extra biosamples
Locations (1)
| Site | City | Country | Site status |
|---|---|---|---|
| Erasmus Medical Center | Rotterdam, South Holland | Netherlands |
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.