Cohort of Patients With Ulcerative Colitis or Polyps Followed in CHU de Bordeaux Associated With a Biocollection - COLIBRI
Not applicable · Testing Blood sample and biopsy · 1 site · University Hospital, Bordeaux
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
This study is testing Blood sample and biopsy (a procedure). Condition(s) listed: Ulcerative Colitis, Inflammatory Bowel Disease (IBD) and Acute Severe Ulcerative Colitis.
Some participants receive a placebo or sham for comparison.
It is open-label: participants know what they are receiving.
This study does not use drug-development phases (it may test a device, diet, procedure, app, or care approach).
Who can join
- Ages 18 and older
- Any sex
Some of the main requirements, copied from the record:
- Inclusion criteria:
- General Inclusion Criteria:
- Patients covered by a social security system.
Plus 13 more requirement(s). Only the trial team can confirm whether you qualify.
What's involved
- About 200 participants are expected to take part.
- Start date: 2025-09 (planned).
- Main results expected around 2027-09 (estimate from the record).
- 1 study site listed in France.
Main thing being measured
- Mayo clinical activity score (Baseline, Month 12)
In the researchers’ words
Ulcerative colitis (UC) is a chronic disease characterized by acute episodes of bloody diarrhea with varying degrees of severity. The most feared event, acute severe UC, can lead to life-threatening and systemic complications.
This is a short automatic summary built from the official record. A fuller plain-English card is coming; until then, please read the official record.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Not yet recruiting |
|---|---|
| Phase | Not applicable |
| Study type | Interventional |
| Conditions | Ulcerative Colitis; Inflammatory Bowel Disease (IBD); Acute Severe Ulcerative Colitis |
| Lead sponsor | University Hospital, Bordeaux |
| Enrollment | 200 (estimated) |
| Start date | 2025-09 |
| Primary completion (est.) | 2027-09 |
| First posted | 2025-07-24 |
| Last updated | 2025-07-24 |
| Official title | Cohort of Patients With Ulcerative Colitis or Polyps Followed in CHU de Bordeaux Associated With a Biocollection - COLIBRI |
| ClinicalTrials.gov ID | NCT07082231 |
Interventions
- Blood sample (Other)
3 blood samples - biopsy (Procedure)
3 pairs of biopsy realised during the coloscopy
Full eligibility criteria (from the record)
* Inclusion criteria:
* General Inclusion Criteria:
* Patients covered by a social security system.
* French-speaking patients.
* Patients aged ≥18 years.
* Patients who have provided free, informed, and written consent (no later than the inclusion day and before any research-related examination).
* Specific Inclusion Criteria for the UC Group:
* Patients diagnosed with ulcerative colitis (UC) according to the European Crohn's and Colitis Organisation (ECCO) guidelines.
* Patients undergoing lower gastrointestinal endoscopy or rectocolic surgery.
* Non-UC Patients with Polyps Group:
* Patients undergoing colonoscopy with resection of hyperplastic polyps in the rectum, sessile serrated lesions, or adenomas >2 cm.
* Exclusion criteria:
* Patients with perianal, ileal lesions, or endoscopic features of colonic lesions suggestive of Crohn's disease.
* Pregnant or breastfeeding women.
* Patients under legal protection or unable to provide informed consent.
* Patients deprived of liberty by judicial or administrative decision, hospitalized without consent, or admitted to a healthcare or social institution for reasons unrelated to the study.Locations (1)
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Bordeaux | Pessac | France |
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.