Predicting Biologic Therapy Success in Ulcerative Colitis Using Intestinal Ultrasound and Fat Assessment
Observational · No treatment assigned · Sites not listed yet · Assiut University
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
Condition(s) listed: Predicting Biologics Success Via VAT Assessment. This is an observational study: researchers collect information (for example questionnaires, samples, or scans) but the study does not assign a treatment.
Who can join
- Ages 18 to 60
- Any sex
Some of the main requirements, copied from the record:
- Any patient above age of 18 years old and diagnosed to have active UC through
- Clinical features: rectal bleeding, with frequent stools and mucous discharge from the rectum. Some patients also describe tenesmus. The onset is typically insidious.
- Endoscopic findings include the following; loss of vascular pattern, Granular and fragile mucosa, friability, ulcerations, erosions, pseudo-polyposis.
There are also 4 reasons someone might not be able to join (exclusion criteria). Only the trial team can confirm whether you qualify.
What's involved
- About 200 participants are expected to take part.
- Start date: 2026-01-01 (planned).
- Main results expected around 2026-09-01 (estimate from the record).
- No study sites are listed yet. Check the official record for contact details.
Main thing being measured
- Change in Visceral Adipose Tissue Volume Measured by abdominal and pelvic CT examination from Baseline to month 6 (Baseline (pre-treatment) and after induction dose (typically 6 month post-initiation of biological therapy) by…)
In the researchers’ words
Our study aimed to detecting biological therapy effectiveness in UC patients using visceral fat assessment
This is a short automatic summary built from the official record. A fuller plain-English card is coming; until then, please read the official record.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Not yet recruiting |
|---|---|
| Phase | Observational |
| Study type | Observational |
| Conditions | Predicting Biologics Success Via VAT Assessment |
| Lead sponsor | Assiut University |
| Enrollment | 200 (estimated) |
| Start date | 2026-01-01 |
| Primary completion (est.) | 2026-09-01 |
| First posted | 2025-08-15 |
| Last updated | 2026-01-07 |
| Official title | Predicting Biological Therapy Effectiveness in Ulcerative Colitis Patients Using Intestinal Ultrasound and Visceral Fat Assessment: A Prospective Study |
| ClinicalTrials.gov ID | NCT07126015 |
Interventions
- None listed
Full eligibility criteria (from the record)
Inclusion Criteria: * Any patient above age of 18 years old and diagnosed to have active UC through * Clinical features: rectal bleeding, with frequent stools and mucous discharge from the rectum. Some patients also describe tenesmus. The onset is typically insidious. * Endoscopic findings include the following; loss of vascular pattern, Granular and fragile mucosa, friability, ulcerations, erosions, pseudo-polyposis. Exclusion Criteria: * Patients with UC who are under age of 18 years old. * Pregnancy. * Previous colectomy. * Patient refuse to participate in the study
Locations (0)
No sites listed yet. The official record has contact information.
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.