TRIOCOL - The Study of Continued Advanced Medical Therapy or Colectomy in Patients With Ulcerative Colitis
Observational · No treatment assigned · 1 site · Region Stockholm
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
Condition(s) listed: Ulcerative Colitis (UC). This is an observational study: researchers collect information (for example questionnaires, samples, or scans) but the study does not assign a treatment.
Who can join
- Ages 18 and older
- Any sex
Some of the main requirements, copied from the record:
- Patients with UC with active disease
- failed at least two lines of advanced medical therapies
- are eligible for both continued AMT and colectomy
There are also 3 reasons someone might not be able to join (exclusion criteria). Only the trial team can confirm whether you qualify.
What's involved
- About 500 participants are expected to take part.
- Start date: 2024-10-22.
- Main results expected around 2028-12-31 (estimate from the record).
- 1 study site listed (1 marked recruiting) in Sweden.
Main thing being measured
- HRQoL at six months (Primary endpoint evaluated six months after enrollement.)
In the researchers’ words
Ulcerative colitis is an inflammatory disease affecting the rectum and colon, most commonly presenting in late adolescence or early adulthood. The primary treatment approach is pharmacological.
This is a short automatic summary built from the official record. A fuller plain-English card is coming; until then, please read the official record.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Recruiting |
|---|---|
| Phase | Observational |
| Study type | Observational |
| Conditions | Ulcerative Colitis (UC) |
| Lead sponsor | Region Stockholm |
| Collaborators | Karolinska Institutet; University Hospital, Linkoeping; Linkoeping University |
| Enrollment | 500 (estimated) |
| Start date | 2024-10-22 |
| Primary completion (est.) | 2028-12-31 |
| First posted | 2026-01-16 |
| Last updated | 2026-01-21 |
| Official title | TRIOCOL - The Study of Continued Advanced Medical Therapy or Colectomy in Patients With Ulcerative Colitis |
| ClinicalTrials.gov ID | NCT07347834 |
Interventions
- None listed
Full eligibility criteria (from the record)
Inclusion Criteria: * Patients with UC with active disease * failed at least two lines of advanced medical therapies * are eligible for both continued AMT and colectomy Exclusion Criteria: * diagnostic uncertainty * diagnosis of impaired cognitive function * non-domestic and non-English speaking
Locations (1)
| Site | City | Country | Site status |
|---|---|---|---|
| Karolinska University Hospital | Solna, Stockholm County | Sweden | Recruiting |
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.