A Pilot Study: Micro and NanoPlastics in Association With Crohn's Disease
Observational · No treatment assigned · 1 site · Mak Wing Yan
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
Condition(s) listed: Crohn's Disease (CD). This is an observational study: researchers collect information (for example questionnaires, samples, or scans) but the study does not assign a treatment.
Who can join
- Ages 18 to 80
- Any sex
Some of the main requirements, copied from the record:
- Cases:
- Age 18-80 years
- Confirmed diagnosis of Crohn's disease (for cases)
Plus 5 more requirement(s). There are also 10 reasons someone might not be able to join (exclusion criteria). Only the trial team can confirm whether you qualify.
What's involved
- About 90 participants are expected to take part.
- Start date: 2026-06-15 (planned).
- Main results expected around 2031-06-30 (estimate from the record).
- 1 study site listed in Hong Kong.
Main thing being measured
- Micro- and nanoparticle abundance between subjects with Crohn's Disease and controls (Cross-sectional when the blood sample and the intestinal biopsy are collected.)
In the researchers’ words
Micro and nanoplastics (MNPs) are environmental contaminants found in food and water. Recent evidence suggests these particles may be linked to intestinal inflammation and changes in gut bacteria, which are key features of Crohn's Disease (CD).
This is a short automatic summary built from the official record. A fuller plain-English card is coming; until then, please read the official record.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Not yet recruiting |
|---|---|
| Phase | Observational |
| Study type | Observational |
| Conditions | Crohn's Disease (CD) |
| Lead sponsor | Mak Wing Yan |
| Enrollment | 90 (estimated) |
| Start date | 2026-06-15 |
| Primary completion (est.) | 2031-06-30 |
| First posted | 2026-06-05 |
| Last updated | 2026-06-05 |
| Official title | Integrated Multi-phase Investigation of Role of Micro and NanoPlastics in Association With Crohn's Disease: Targeting Microbiome, Immunity, and Barrier Dysfunction: A Pilot Study |
| ClinicalTrials.gov ID | NCT07630883 |
Interventions
- None listed
Full eligibility criteria (from the record)
Inclusion Criteria: Cases: * Age 18-80 years * Confirmed diagnosis of Crohn's disease (for cases) * Ability to provide informed consent. Control: * Age 18-80 years old * No history of major large bowel resection * Ability to provide informed consent. Exclusion Criteria: Cases: * Antibiotic/probiotic use within 4 weeks * History of gastrointestinal malignancy * Presence of stoma * Currently Pregnant * Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure Control: * Currently Pregnant * Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure * Inability in giving consent
Locations (1)
| Site | City | Country | Site status |
|---|---|---|---|
| Prince of Wales Hospital | Hong Kong | Hong Kong |
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.